303.

Evans JL, Ali R. Calcium utilization and feed efficiency in the growing rat as affected by dietary calcium, buffering capacity, lactose and EDTA. J Nutr. 1967; 92(4):417-424. (BA49) [An experiment was designed to study the relationships of Ca, buffering capacity (BC), lactose and ethylenediaminetetraacetic acid (EDTA) in the nutrition of the growing rat. For the replicated, factorially arranged experiment, which involved Ca (0.19, 0.48 and 0.78%), buffer capacity (BC 1, 0.46, BC 2, 0.54, and BC 3, 0.76 ml of 1 N HCl required to reduce the pH of 5.0 g of the diet by one pH unit), lactose (0 and 12%), and EDTA (0 and 0.2%), 152 rats were used. Dihydrogen-to-monohydrogen phosphate ratios were varied to produce the different BC's, and a constant P (0.4%) was provided for all diets. As dietary Ca increased from 0.19 to 0.48%, retention and deposition of Ca in the total body and in the femur and efficiency of feed conversion showed improvement. However, 0.78% Ca did not prove beneficial over 0.48% Ca. The diets which produced the most acidic condition (BC 1) in the stomach, resulted in the most improved Ca retention, feed intake and efficiency of feed conversion. As judged from the reduced fecal Ca with BC 1 diets, the calculated increase in urinary Ca was not great enough to offset the increased Ca absorption in the intestine. Lactose increased Ca retention and improved bone calcification, and, for the total 6-week experimental period, EDTA decreased the retention and deposition of Ca.]

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