424.

Valverde A, Murillo A. Endogenous excretion of calcium: effects of sodium oxalate, sodium citrate, sodium lactate and EDTA. Ars. Pharm. 1978; 19(4): 353-360. (CA) [In rats, administration of a diet contg. 0.56% Na oxalate (I) resulted in a 6-fold increase in the fecal excretion of Ca along with a marked decrease in the Ca excretion in urine. Probably, I induces endogenous Ca pptn., thus impairing its reabsorption. These effects were not influenced by the age or wt. of the exptl. animals. When Na citrate or EDTA were added at 3 and 0.3%, resp., increased fecal and urinary Ca excretion was obsd., whereas Na lactate addn. to the diet increased urinary Ca and did not alter fecal Ca.]

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